REVERSE AGING:
OPTIMIZE SKIN HEALTH † ENHANCE COLLAGEN PRODUCTION † SUPPORT DNA REPAIR † CLEAR DAMAGED CELLS † BOOST IMMUNE FUNCTION †

SLOW AGING AT THE CELLULAR LEVEL.

Combat visible signs of aging. Brighten your complexion. Support your skin’s defense against UV exposure.

AC-11® is a patented, clinically proven extract that targets aging at its core—deep within your cells. It clears damaged cells, enhances your body's natural capacity to repair DNA, protects skin from oxidative stress, and boosts collagen production. This layered, holistic support smooths and revitalizes your skin.†

PROMOTES SKIN HEALTH

Boosts type III collagen production for youthful, radiant skin†

ENHANCES DNA REPAIR

Supports the body’s natural DNA repair processes†

SUPPORTS TELOMERE HEALTH

Maintains telomere integrity to support healthy aging at the cellular level†
ac-11_0df75793-1228-42b2-aa8a-0c0c4652c69f
3_14ddfa28-c637-4ff5-a6af-1e4c23a3d6c9
Transform Your Skin!

Is Your Skin Showing Signs of Aging?

Dark Spots?
Fine Lines?
Wrinkles?
Crepey or Sagging Skin?
Hollowing Around the Eyes and Face?

These are the unmistakable signs.

Your cells are overwhelmed... 

Your body is struggling to repair its DNA...

So, your body’s collagen production is slowing down.

And the visible effects of aging are becoming harder to ignore. 

While aging is a natural part of life, external factors drastically accelerate the process. 

Every day, your skin is under relentless attack—from harmful UV rays, pollution, stress, poor lifestyle choices, and other environmental disruptors.

These stressors not only accelerate aging but can also leave your skin looking dull, tired, and older than you feel:

DAILY SUN EXPOSURE

TOXINS & POLLUTION

POOR LIFESTYLE CHOICES

STRESS & INFLAMMATION

Breakthrough Solution for Aging Skin

But if you're ready to hit pause on aging and take back control... 

It’s time to discover a science-backed solution that reverses aging at the cellular level. 

This powerful miracle from the rainforest maximizes your cells' full potential... 

Igniting your body's collagen production—restoring that youthful glow while also supporting joints and connective tissues. 

At the same time, it defends your entire body against toxins and cellular damage, tackling aging at its very source. 

Most importantly, it helps your body to repair its own precious DNA—the very blueprint of life—empowering you to fight back against Father Time. 

Why wait to gain powerful anti-aging cellular support? 

Unlock this 20-second-a-day ritual that can transform your skin from the inside out.

Imagine waking up each morning to smoother, firmer, and more radiant skin—feeling confident and rejuvenated. 

But to experience these incredible benefits, you need to take that first step.

Take Control in 3 Simple Steps:

Try AC-11® CAT'S CLAW

Begin your journey to restore your skin’s radiance and reverse visible signs of aging—from the inside out.

SEE VISIBLE RESULTS, FAST!

Wake up to smoother, firmer, more youthful skin in just 3 months or less!

CLAIM YOUR LIMITE OFFER

Transform Your Skin Today – And Save 30%!

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INTRODUCING: AC-11® CAT'S CLAW

The world’s first and only patented, clinically studied Cat’s Claw extract—AC-11®—provides long-term support for aging that's beyond skin deep.

It works deep within your body at the cellular level to help you look AND FEEL your best.

Here’s how:

Imagine waking up to smoother, younger-looking skin every day, knowing you’re addressing aging at its root—within your DNA. 

With AC-11®, this is possible. 

Think of it as a deep cellular detox, benefiting not just your skin but your entire body. 

Picture this powerful Amazonian plant extract supercharging your body's ability to clear toxic junk from every cell simultaneously. 

Our clinically proven Cat's Claw extract repairs damaged DNA, reduces sun-induced skin damage, and boosts type-III collagen production for a glowing, youthful complexion. 

It restores, rejuvenates, and revitalizes your skin by targeting aging where it matters most—within your cells. 

AC-11® isn’t just any plant extract. 

AC-11® sets the bar for safety, purity, and clinical efficacy, with over 20 years of research, 11 patents, and validation from 42 clinical studies.

Our team at Proof, along with tens of thousands of satisfied users, can attest to its transformational results—typically in 90 days or less. 

By naturally clearing toxic cellular waste, AC-11® not only protects and improves your skin’s appearance but also delivers a wide range of full-body benefits:

SUPPORTS DNA REPAIR

Enhances your body’s natural ability to repair its own DNA †

PROMOTES SKIN HEALTH

Boost type III collagen synthesis to smooth out fine lines and wrinkles†

AIDS TELOMERE HEALTH

Promotes cellular health by maintaining telomere length during cell division†

INFLAMMATION MANAGEMENT

Supports a healthy inflammatory response for your skin and entire body†

ENHANCES IMMUNE HEALTH

Strengthens immune function by extending the lifespan of white blood cells†

SUPPORTs BRAIN HEALTH

Protects neural health from damage caused by environmental stressors†

And the best part?

Achieving all this couldn’t be simpler. 

Unlike your skincare routine...

It only takes SECONDS A DAY to reverse aging at the cellular level with our convenient-one a-day! 

Just take one 700 mg dose of AC-11® Cat's Claw daily with a glass of water.
bg-loobook
And let the revolutionary science of AC-11® Cat’s Claw inner bark extract work its magic.

That's all there is to it...

Only Proof Vitality’s patented Cat’s Claw extract allows you to experience profound anti-aging benefits from the inside out:

  • Support DNA repair †

    Enhance your body's ability to repair its DNA, optimizing cellular function ad reversing the signs of aging at the cellular level. †

  • Clear damaged cells †

    Remove damaged, senescent cells to promote healthier cellular function and slow both visible and internal signs of aging. †

  • Boost Collagen †

    Reduce the appearance of fine lines and wrinkles while supporting healthy joints by enhancing your body’s ability to synthesize new type-III collagen. †
Experience an incredible transformation, inside and out. 

 Next, let’s explore the factors that accelerate cellular aging and how AC-11® Cat’s Claw can help turn back the clock.

WHAT CAUSES PREMATURE AGING?

Aging is a natural and inevitable process, but many lifestyle and environmental factors can speed it up, causing premature damage to your cells and skin. 

When these factors accelerate the aging process, it affects how we look and feel long before our time. 

Here’s what can cause your biological clock to speed up:

UV Exposure from Sun

Sunlight is one of the most significant culprits. Constant exposure to UV rays breaks down collagen and elastin in your skin, leading to wrinkles, sagging, and dark spots. 

Over time, UV light accelerates the appearance of aging, leaving skin thinner, rougher, and less elastic.

Stress

Chronic stress releases cortisol, which impacts your cells’ ability to regenerate properly. 

This weakens your immune system and interferes with the body’s natural aging defenses. 

Prolonged stress leaves its mark on your skin, resulting in premature wrinkles, dryness, and fatigue.

Poor Diet and Inflammation

Processed and sugary foods can cause oxidative stress, damaging your cells and causing your telomeres—the protective caps on your DNA—to shorten. 

This speeds up cellular aging, causing sagging skin, inflammation, and loss of vitality.

Smoking

Smoking reduces oxygen flow to the skin, which starves your cells and leads to sagging, wrinkled skin. 

The harmful toxins in cigarettes also destroy collagen, causing your skin to age faster than it should.

Environmental Toxins and Pollution

Exposure to environmental pollutants, such as chemicals, heavy metals, air pollution, and radiation, plays a significant role in accelerating the aging process. 

These toxins damage cells and degrade telomeres—the protective caps on our DNA that preserve cellular health during replication. 

As telomeres shorten due to this constant toxic exposure, cells lose their ability to regenerate, leading to premature aging and increased susceptibility to age-related diseases. 

Maintaining telomere length is vital for slowing down this process, and AC-11® helps preserve telomeres during cell division, protecting your cells from the harsh effects of environmental pollutants.

THE HIDDEN DANGERS OF TOXIC SKINCARE PRODUCTS

Did you know that women spend an average of $3,756 per year on beauty products and services, while men spend an average of $2,928.

But when it comes to your skin, not all products are created equal.

You may be unknowingly speeding up aging.

Many popular cosmetics and skincare products are loaded with harmful chemicals that can damage your skin and accelerate aging over time. 

These toxic ingredients, hidden in everyday products, have been linked to serious health concerns, including cancer, reproductive harm, and even DNA damage. 

Shocking, right? 

 Some of the most harmful substances include:

Formaldehyde

And its derivatives are known carcinogens that have no place in skincare.

Phthalates

Hormones disruptors that have been linked to reproductive issues.

PFAS

A group of chemicals tied to cancer and immune system dysfunction.

Parabens

Endocrine disruptors that interferes with your body’s natural processes.

Label Disclosure?

Even worse, many of these chemicals don’t have to be disclosed on labels, hiding under terms like “fragrance.” 

Over time, exposure to these toxic ingredients can cause chronic skin damage, lead to premature wrinkles, and put your long-term health at risk.
That’s why we believe in beauty from within. AC-11® offers a natural, safe way to support your skin and overall health from the inside out. 

By protecting your cells, stimulating collagen production, and maintaining telomere length, AC-11® helps slow the visible signs of aging and restores your skin’s natural vitality—by helping eliminate harmful toxins.

AC-11®: Powerful Anti-Aging for Your Skin and Your Whole Body

DNA Repair and Slowing Aging †

As we covered earlier...

The true cause of aging is the degradation of cell health over time. 

We can’t see it happening at the cellular level, but unfortunately, we see and feel the effects as sagging skin, age spots, achy joints, brain fog, loss of energy, and a general decrease in quality of life. 

Our AC-11® supplement enhances your body's natural DNA repair capacity to combat accelerated aging and help slow normal biological aging, keeping you healthier longer.† 

Addressing DNA Damage †

Every day, our bodies endure up to one million instances of DNA damage caused by free radicals.

Your body has antioxidants to help block these free radicals and prevent DNA damage, but this system declines as you age. 

While you’re young and healthy, your body’s antioxidants and enzymes work together to block free radicals and repair DNA damage as it occurs, but this protective system declines with age.

This process accelerates with overexposure to the sun, an unhealthy lifestyle, smoking, or contact with environmental toxins and pollution, taking a toll on your body from the inside out.

AC-11® enhances your body's natural ability to block free radicals and limit DNA damage with its powerful antioxidant activity.†

Healthy Cell Turnover †

When cells become damaged over time, they cannot function properly. 

They secrete compounds that damage surrounding cells, accelerating overall cell damage. 

Your body has a natural process called apoptosis that causes it to kill off these damaged cells to preserve surrounding cells and keep the rest of the body healthy. 

 AC-11® helps to support your body's natural apoptosis mechanisms.† 

Boost Type-3 Collagen Production †

Healthy, supple skin comes from within. AC-11® stimulates the production of type-3 collagen, which plays a key role in maintaining skin elasticity, smoothness, and resilience. 

By boosting this collagen type, AC-11® helps reduce the appearance of fine lines and wrinkles while promoting youthful, radiant skin. 

Type-3 collagen also supports the structural integrity of your skin and connective tissues, ensuring long-lasting beauty from the inside out.† 

Enhance Immune Function †

A strong immune system is key to slowing the aging process and maintaining overall health. As we age, our immune systems weaken, making us more susceptible to illness and inflammation, which accelerates cellular damage. 

 AC-11® enhances immune function by extending the life cycle of white blood cells, helping your body fight off infections more effectively. 

By supporting healthier immune communication and reducing the impact of dysfunctional immune cells, AC-11® helps keep your body in peak condition, promoting healthy aging from the inside out.†

AC-11® IS DIFFERENT THAN STANDARD CAT'S CLAW

CAEs — NOT ALKALOIDS

Not all Cat’s Claw extracts are created equal. 

While most products on the market are crude or standardized to alkaloids, AC-11® is in a league of its own. 

What sets AC-11® apart is its standardization to 8% Carboxy Alkyl Esters (CAEs)—the active compounds responsible for 90% of its therapeutic benefits. 

Unlike alkaloids, which other extracts rely on, CAEs are the powerhouse behind AC-11®’s unique ability to support DNA repair, cellular health, and skin rejuvenation.

Backed by Over 20 Years of Research

AC-11® isn’t just another Cat’s Claw extract; it’s the result of two decades of rigorous research and development. 

With studies proving its efficacy, AC-11® has been shown to:

SUPPORT DNA REPAIR

Support the body’s natural DNA repair processes†

PROMOTE SKIN HEALTH

Boost type III collagen production for youthful, radiant skin†

TELOMERE HEALTH

Maintain telomere integrity to support healthy aging at the cellular level†

INFLAMMATION MANAGEMENT

Supports a healthy inflammatory response for your skin and entire body†

IMMUNE HEALTH

Strengthen immune function by extending the lifespan of white blood cells†

SUPPORT BRAIN HEALTH

Protect neural health from damage caused by environmental stressors†

Environmentally Conscious

SUSTAINABLY HARVESTED

AC-11® is harvested from the inner bark of Uncaria tomentosa, sourced sustainably from the Amazon rainforests of Brazil and Peru.

ECO-FRIENDLY

Using eco-friendly and renewable processes, we ensure that this powerful extract not only supports your health but also protects the environment.

Enhance Beauty from Within. Feel your best.

AC-11® is not your typical Cat’s Claw—it’s a scientifically advanced plant extract that promotes healthy aging from within. 

When you choose AC-11®, you’re investing in a product proven to support skin health, immune resilience, and DNA repair, ensuring you age gracefully while protecting your cellular vitality. 

And it does this from the inside out—providing full-body support all the way down to the cellular level. 

If you're serious about taking control of your health, now is the time to invest in the one-of-a-kind power of AC-11®.

THE PROOF VITALITY STANDARD

Hi, I'm Fon Walters, Founder and Chief Product Officer of Proof Vitality.

Our mission is simple: to help you age better—so you look and feel your best, get the most out of every moment, and live your life to its fullest. 

We believe that starts at the cellular level, where aging truly begins. 

At Proof Vitality, we only offer patented, clinically studied ingredients at science-based dosages. 

We cut no corners. Our goal is to deliver evidence-based supplements you can trust, and it’s personal for us—we don’t just sell these products, we take them too. Our families rely on them just like you do. 

For the last two decades, I’ve worked in the supplement industry, learning from top experts and leading brands. Before founding Proof Vitality, I spent over a decade with Whole Foods Market, gaining invaluable insights into what truly makes a difference in health and wellness. 

We know you don’t have time to research the most effective, science-backed ingredients in the world. 

That’s why we do the work for you. After reviewing hundreds of ingredients for healthy aging, one stood out above the rest—AC-11® Cat’s Claw. It had to be part of our product eco system. 

We’ve built Proof Vitality to give you the tools to optimize your aging process, both in how it looks and feels. 

Aging skin, declining energy, and slowing performance are real concerns, but they don’t have to control your life. 

With our products, we aim to help you fight back. 

Aging better isn’t just possible—it’s my life's mission to make it a reality for you. 

Fon Walters 
Chief Product Officer
Proof Vitality

Safe, Pure, and Effective.

Every bottle of AC-11® Cat's Claw is manufactured in the USA at our state-of-the-art FDA-approved, GMP (Good Manufacturing Practices) facility, adhering to the highest standards of purity and safety. 

AC-11® is 100% natural, free from fillers, soy, gluten, preservatives, artificial colors, and GMOs. Backed by over 20 years of research and development, AC-11® is proven to repair sun-damaged skin, restore cellular function, and support healthy aging.
ac-11_0c4b480f-6da3-4a35-88f7-f4e770363567

Clinically Studied

Science-based Dosages

100% Vegetarian

Patent Protected

Produced in cGMP Facility

Manufactured in the USA

AC-11® Cat's Claw: 20 Years Raising the Bar
With 11 patents and 42 clinical studies, AC-11® sets the benchmark for clinically-studied healthy aging supplements. Proof Vitality ensures you get a full 700 mg dose in just one easy-to-take capsule daily, helping you stay on track with your health and beauty goals.
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Daily Dosage
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Transformative Results
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Clinical Studies
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International Patents

Right now, you can join our Subscribe and Save program to receive a bottle of AC-11® every 30 days for just $34......

YES, JUST $34.99 / MONTH!

Before you place your order, it’s important to know that research shows taking 700 mg of AC-11® daily for at least 90 to 180 days delivers optimal, long-lasting results. 

The science is clear: the longer and more consistently you take Proof Vitality's patented cat's claw extract, the more profound the benefits will be. 

To ensure you experience the most transformative, life-changing results possible, we're giving you an exclusive opportunity to secure 90 days' worth of AC-11® or join our Subscribe and Save program at an unbeatable price. 

With our Subscribe and Save option, you can lock in a lifetime subscription and get AC-11® for just $34.99 a month, saving you $15 every month—up to $180 a year! 

FREE SHIPPING!

This special pricing is guaranteed today, but only while supplies last. 

Our inventory is moving faster than anticipated due to the incredible demand for these bundle and save deals and our top deal—our lifetime subscription bonus. 

If these savings are still available, I highly recommend taking advantage of them now before they’re gone. 

And just to be clear...

You’ll Never Be Able to Buy AC-11® Cat's Claw Cheaper than Today…

And remember, Proof Vitality's AC-11® Cat's Claw isn’t available for purchase anywhere else—not on Amazon, in stores, or on any other website.

We’re able to offer you today’s unbeatable pricing because we’ve partnered directly with an industry-leading manufacturer and dropshipping supplier. This allows us to ship directly to you—quickly and efficiently.

Rest assured, there are no hidden fees or charges whatsoever.

So, if AC-11® is still available, you’ll see the table below offering three exclusive, money-saving options. Simply select your package, click the 'BUY NOW' or better yet, the 'SUBSCRIBE & SAVE' button, and proceed to our 256-bit secure order page.

After filling in your details on our 100% safe and secure order form, we’ll get your package shipped straight to your door—right away.

To make your decision even easier, we’re including a 30-day, no-questions-asked, 100% money-back guarantee.

Trying AC-11® is completely risk-free—there’s nothing to lose and everything to gain!

30_Day_Money_Back
AC-11® is backed by a 30 day, no questions asked, 100% money back guarantee. 

If trying our patented cat's claw extract doesn’t turn out to be the best decision you’ve ever made, or if you change your mind for any reason whatsoever, just let us know any time in the next 30 days and we’ll issue you a prompt and courteous refund right away. 

Our industry-leading customer care team and myself are extremely easy to get a hold of and will always be here to support you no matter what.
I really want you to have this 30-day, no-questions-asked, 100% money-back guarantee to make trying AC-11® Cat's Claw an absolute no-brainer for you. 

There’s simply no risk to you. 

Select your money-saving package below, and I can’t wait to hear how AC-11 work for you!

End of Summer Sale: AC-11®
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30_Day_Money_Back
This product is backed by a 100% money-back guarantee for 30 full days from your original purchase. If you're not totally and completely satisfied with this product, your results, or your experience in the first 30 days from your purchase, simply let us know by dropping us an email, and we'll give you a full refund within 48 hours of the product being returned. That's right, simply return the unused product anytime within 30 days of your purchase, and you'll receive a full, no-questions-asked refund (less shipping and handling).

AC-11® Cat's Claw FAQs

What is ac-11®?

AC-11® is a safe, all-natural, and highly effective aqueous extract of Cat’s Claw (Uncaria tomentosa), a traditional medicinal plant indigenous to the Amazon rainforest. 

AC-11® is radically different from other Cat’s Claw extracts as it is practically free of alkaloids. 

Standardized to a minimum of 8% Carboxy Alkyl Esters (CAEs), research demonstrates AC-11®'s natural ability to help the body repair its DNA. 

Additional studies have also shown AC-11®’s ability to support the body’s inflammatory response, help rid the body of damaged cells, enhance immune function, and decrease the rate of telomere truncation.

Is ac-11® truly clinically studied and backed by science?

Yes. AC-11® is supported by 42 clinical studies, which demonstrate its efficacy in both oral and topical applications. These studies provide scientific evidence of its benefits and effectiveness.

What is DNA?

DNA (deoxyribonucleic acid) is the self-replicating molecule that contains the genetic instructions essential for the functioning, development, growth, and reproduction of nearly all living organisms.

Is DNA important to our health?

Yes, DNA is crucial to our health. It contains the genetic instructions that drive all bodily processes and is essential for the optimal functioning of every cell. 

Damage to DNA can lead to cellular mutations, which disrupt critical biological processes and contribute to accelerated aging. Additionally, DNA damage is linked to various age-related diseases.
How does natural DNA repair work?
Natural DNA repair involves several enzymatic processes that address damage caused by oxidative and non-oxidative stress. 

These homeostatic processes help maintain genetic integrity and cellular function, preserving the body’s natural equilibrium. 

Effective DNA repair processes contribute to longer, healthier lives by minimizing the impact of DNA damage and supporting overall cellular health.
What is Aging?
Aging is the natural, time-related deterioration of the body’s biological functions, which impairs its ability to efficiently clear cellular toxicity and repair damaged DNA. 

This accumulation of DNA damage leads to visible signs of aging, such as wrinkled or sagging skin, cognitive decline, and weakened immune function.
Do our genes predetermine our lifespans and genetic inheritance?
Not entirely. While our DNA can influence our risk for certain conditions, it does not determine our exact aging process or guarantee that we will experience the same diseases as our family members. 

We can mitigate the effects of detrimental lifestyle and environmental factors that may accelerate aging or trigger genetic-related diseases. 

By avoiding excessive sun exposure, smoking, excessive alcohol consumption, and toxic pollutants, we can reduce cellular damage. 

Additionally, maintaining a diet rich in antioxidants, managing daily stress, and smartly supplementing our nutrition can help minimize daily DNA damage and enhance our cells’ natural repair mechanisms. 

 However, damage to cells and DNA that has already occurred cannot be reversed. 

AC-11® is the first and only known plant extract proven to enhance the body's DNA repair ability.
How does AC-11® work?
AC-11® enhances your body's natural ability to repair its DNA. 

It may activate critical DNA repair enzymes found on Chromosome 11, which play a vital role in the body’s DNA repair process. 

By supporting these enzymes, AC-11® helps facilitate and optimize your body’s natural DNA repair mechanisms.
Why should I take ac-11®? What are the benefits?
Backed by 42 clinical studies (and counting), AC-11® offers numerous potential benefits, including: Supports Natural DNA Repair: 

Helps combat accelerated aging by supporting the body’s ability to repair its own DNA. 

Repairs Skin Damage: Aids in repairing skin damage from excessive sun exposure. Boosts 

Boosts Immune Function: Enhances immune function by promoting the longevity of white blood cells. 

Supports Neural Function: Helps repair damage to neural function caused by high-decibel noise exposure. 

Promotes Healthy Inflammation Response: Encourages a balanced inflammatory response, which may reduce pro-inflammatory cytokines. 

Maintains Telomere Integrity: Supports the maintenance of telomere length and integrity during cell division. 

Enhances Collagen Production: Boosts the production of natural collagen III, contributing to soft, supple, youthful-looking skin. 

Lab Tested | Gluten Free | Non-GMO | No Junk

Why is AC-11® Radically Different from Other Cat's Claw Extracts?
AC-11® stands out as the only known extract of Uncaria tomentosa specifically shown to support the body’s natural DNA repair processes. 

This unique therapeutic benefit is supported by 42 clinical studies and multiple patents. 

AC-11® features a distinctly low-weight, alkaloid-free molecular composition (less than 10,000 Daltons), thanks to its patented ultra-filtration aqueous extraction process. 

This results in a highly bioavailable, safe, and effective supplement for long-term use. 

In contrast, most generic “cat’s claw” extracts on the market are not backed by substantial research. 

They are typically water-insoluble and alkaloid-based, and may exhibit mild toxicity with prolonged use.

Is AC-11® Manufacturing Quality Controlled?
Yes, AC-11® is produced in an ISO 9002-certified facility that operates under strict FDA regulations and adheres to GMP (Good Manufacturing Practices) standards. 

Each batch of AC-11® is lab-tested and meets all industry standards to ensure the highest levels of safety, purity, and efficacy.

Is AC-11® Safe?
Yes, AC-11® has been proven to be safe when consumed in amounts up to 8,000 mg. 

The recommended daily dose for adults weighing between 120 and 200 pounds (70-90 kg) is between 350 and 700 mg.

Can I Take AC-11® With My Medications?
We recommend consulting your healthcare practitioner if you are pregnant, nursing, or taking medication. 

However, AC-11® has been shown through CYP analysis to not negatively interact with common pharmaceuticals, making it generally safe to use alongside other medications.

Is AC-11® Patent Protected?
Yes, AC-11® is protected by 11 patents, which cover its unique technology, composition, active ingredients, and a range of health benefits.

Does AC-11® Contain Artificial Ingredients?
No, AC-11® is completely natural and does not contain any artificial ingredients. It is made with all-natural components, including its carrier, Manioc Maltodextrin.

Is AC-11® Environmentally Sustainable?
Yes, AC-11® is produced with strict adherence to the Floravida Institutes of Brazil’s guidelines for biodiversity, environmental conservation, and community inclusion. 

The extract is sourced from the inner bark of Cat’s Claw (Uncaria tomentosa) using sustainable harvesting practices. 

The bark is collected about three feet above the ground to preserve the plant’s health. 

Additionally, the plant is capped to protect the root structure and encourage rapid vine regeneration. 

To ensure ongoing viability, new Cat’s Claw seedlings are planted in the harvesting area.

End of Summer Sale: AC-11®
Save Up to 30% Today!

1 BOTTLE

30 DAY SUPPLY
ac-11_0c4b480f-6da3-4a35-88f7-f4e770363567
$49
PER BOTTLE
YOU SAVE $10

3 BOTTLES

90 DAY SUPPLY
AC-11_3-pack-2
$39
PER BOTTLE
($117 + TAX)
YOU SAVE $60
+FREE SHIPPING

SIGN UP!

AND SAVE $15/MONTH!
ac-11_0c4b480f-6da3-4a35-88f7-f4e770363567
$34.99
PER MONTH + TAX
SUBSCRIBE & SAVE
YOU SAVE $180/YEAR!
+FREE SHIPPING!!

LIMITED TIME OFFER! 

*Special pricing not guaranteed past today!

Free shipping on domestic orders over $100!

30_Day_Money_Back
This product is backed by a 100% money-back guarantee for 30 full days from your original purchase. If you're not totally and completely satisfied with this product, your results, or your experience in the first 30 days from your purchase, simply let us know by dropping us an email, and we'll give you a full refund within 48 hours of the product being returned. That's right, simply return the unused product anytime within 30 days of your purchase, and you'll receive a full, no-questions-asked refund (less shipping and handling).
† The statements on this website have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, please consult your healthcare practitioner before using our products.

AC-11® Cat's Claw References

DNA Repair, Cellular Health, Anti Aging, Life Span, & Health Span

1. Sheng Y, Li L, Holmgren K, Pero RW. DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study. Phytomedicine. 2001 Jul;8(4):275-82. doi: 10.1078/0944-7113-00045. PMID: 11515717.

2. Pero, R. W., Hoppe, C., & Sheng, Y. (2000). Serum Thiols as a Surrogate Estimate of DNA Repair Correlates to Mammalian Life Span. Journal of Anti-Aging Medicine. https://doi.org/10.1089/rej.1.2000.3.241

3. Banne AF, Amiri A, Pero RW. Reduced level of serum thiols in patients with a diagnosis of active disease. J Anti Aging Med. 2003;6(4):327-34. doi: 10.1089/109454503323028920. PMID: 15142434.

4. Tilstra JS, Robinson AR, Wang J, Gregg SQ, Clauson CL, Reay DP, Nasto LA, St Croix CM, Usas A, Vo N, Huard J, Clemens PR, Stolz DB, Guttridge DC, Watkins SC, Garinis GA, Wang Y, Niedernhofer LJ, Robbins PD. NF-κB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest. 2012 Jul;122(7):2601-12. doi: 10.1172/JCI45785. Epub 2012 Jun 18. PMID: 22706308; PMCID: PMC3386805.

5. Akesson Ch, Pero RW, Ivars F. C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo. Phytomedicine. 2003 Jan;10(1):23-33. doi: 10.1078/094471103321648629. PMID: 12622460.

6. Pero RW, Amiri A, Sheng Y, Welther M, Rich M. Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements. Phytomedicine. 2005 Apr;12(4):255-63. doi: 10.1016/j.phymed.2004.01.008. PMID: 15898702.

7. Pero, R. W., Giampapa, V. C., & Vojdani, A. (2002). Comparison of a Broad Spectrum Anti-Aging Nutritional Supplement with and without the Addition of a DNA Repair Enhancing Cat’s Claw Extract. Journal of Anti-Aging Medicine. https://doi.org/10.1089/109454502763485467

8.Pero, R. W. (2009, September 1). In vivo treatment of humans with quinic acid enhances DNA repair and reduces the influence of lifestyle factors on risk to disease. Document – Gale Academic OneFile. https://go.gale.com/ps/i.do?id=GALE%7CA215925274&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=09732691&p=AONE&sw=w&userGroupName=anon%7E6ddd846

9. Guthrie OW. Dynamic compartmentalization of DNA repair proteins within spiral ganglion neurons in response to noise stress. Int J Neurosci. 2012 Dec;122(12):757-66. doi: 10.3109/00207454.2012.721828. Epub 2012 Oct 16. PMID: 22900489.

Immune Health, Inflammation Response, Apoptosis, & Cellular Senescence

10. Sheng Y, Pero RW, Amiri A, Bryngelsson C. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anticancer Res. 1998 Sep-Oct;18(5A):3363-8. PMID: 9858909.

11. Sheng Y, Bryngelsson C, Pero RW. Enhanced DNA repair, immune function and reduced toxicity of C-MED-100, a novel aqueous extract from Uncaria tomentosa. J Ethnopharmacol. 2000 Feb;69(2):115-26. doi: 10.1016/s0378-8741(99)00070-7. PMID: 10687868.

12. Sheng Y, Pero RW, Wagner H. Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa. Phytomedicine. 2000 Apr;7(2):137-43. doi: 10.1016/S0944-7113(00)80086-0. PMID: 10839217.

13. Lamm S, Sheng Y, Pero RW. Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble extract of Uncaria tomentosa, C-Med-100. Phytomedicine. 2001 Jul;8(4):267-74. doi: 10.1078/0944-7113-00046. PMID: 11515716.

Brain Health, Neurological Support, Cognitive Function, Hearing

14. Guthrie OW, Gearhart CA, Fulton S, Fechter LD. Carboxy alkyl esters of Uncaria tomentosa augment recovery of sensorineural functions following noise injury. Brain Res. 2011 Aug 17;1407:97-106. doi: 10.1016/j.brainres.2011.06.044. Epub 2011 Jun 24. PMID: 21762882.

15. Guthrie, O. W., & Xu, H. (2013b). Reduced Phosphorylation of Histone Variant H2Ax in the Organ of Corti is Associated with Otoprotection from Noise Injury. Otolaryngology, 03(01). https://doi.org/10.4172/2161-119x.1000131

16. Guthrie OW. Preservation of Neural Sensitivity after Noise-Induced Suppression of Sensory Function. J Am Acad Audiol. 2016 Jan;27(1):49-61. doi: 10.3766/jaaa.15047. PMID: 26809326.

17. Shi Z, Lu Z, Zhao Y, Wang Y, Zhao-Wilson X, Guan P, Duan X, Chang YZ, Zhao B. Neuroprotective effects of aqueous extracts of Uncaria tomentosa: Insights from 6-OHDA induced cell damage and transgenic Caenorhabditis elegans model. Neurochem Int. 2013 Jun;62(7):940-7. doi: 10.1016/j.neuint.2013.03.001. Epub 2013 Mar 14. PMID: 23500604.

Safety, Efficacy, Functionality

18. Montoro P, Carbone V, Quiroz Jde D, De Simone F, Pizza C. Identification and quantification of components in extracts of Uncaria tomentosa by HPLC-ES/MS. Phytochem Anal. 2004 Jan-Feb;15(1):55-64. doi: 10.1002/pca.740. PMID: 14979528.

19. Akesson C, Lindgren H, Pero RW, Leanderson T, Ivars F. Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100. Int Immunopharmacol. 2005 Jan;5(1):219-29. doi: 10.1016/j.intimp.2004.09.028. PMID: 15589483.

20. Sheng Y, Akesson C, Holmgren K, Bryngelsson C, Giamapa V, Pero RW. An active ingredient of Cat’s Claw water extracts identification and efficacy of quinic acid. J Ethnopharmacol. 2005 Jan 15;96(3):577-84. doi: 10.1016/j.jep.2004.10.002. Epub 2004 Dec 8. PMID: 15619581.

21. Historical Development of Uncaria Preparations and Their Related bioactive Components. novapublishers.com.(Pero: Nova Sciences Publishers, Chapter 10, 2010)

22. McDonnell AM, Dang CH. Basic review of the cytochrome p450 system. J Adv Pract Oncol. 2013 Jul;4(4):263-8. doi: 10.6004/jadpro.2013.4.4.7. PMID: 25032007; PMCID: PMC4093435.

Antioxidant Potential

23. Brunswick Labs, Certificate of Analysis, ORAC Value results for ac-11®

24. Pero RW, Lund H, Leanderson T. Antioxidant metabolism induced by quinic acid. Increased urinary excretion of tryptophan and nicotinamide. Phytother Res. 2009 Mar;23(3):335-46. doi: 10.1002/ptr.2628. PMID: 18844285.

25. Pero RW, Lund H. Dietary quinic acid supplied as the nutritional supplement AIO + AC-11® leads to induction of micromolar levels of nicotinamide and tryptophan in the urine. Phytother Res. 2011 Jun;25(6):851-7. doi: 10.1002/ptr.3348. Epub 2010 Nov 22. PMID: 21104945.

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